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For centuries, red wine has been linked to numerous health benefits. But this new study, published online in the journal Nature, shows that mammals given ultrahigh doses of resveratrol benefit from positive effects of cutting calories without actually doing it. "If we're right about this, it would mean you could have the benefit of restricting calories without having to feel hungry," Sinclair said. "It's the Holy Grail of aging research."

Dr. Brent Bauer, director of the Department of Internal Medicine's Complementary and Integrative Medicine Program at Mayo Clinic says "This may be the best thing since sliced bread for human beings, but we just don't know yet." This research, funded in part by the National Institute on Aging, was published in the journals Nature and Cells in November, and bottles of resveratrol have been selling like wildfire ever since.

Resveratrol is the ingredient in red wine that made headlines in November 2007 when scientists demonstrated that it kept overfed mice from gaining weight, turned them into the equivalent of Olympic marathoners, and seemed to slow down their aging process. Few medical discoveries have generated so much instant buzz.

Resveratrol is one of a group of antioxidant compounds called polyphenols found in red wine that has been reported to have anti-inflammatory as well as anticancer properties. Red Wine Ingredient May Delay Aging Resveratrol May Prolong Life and Fight Age-Related Diseases. Resveratrol, may counter type 2 diabetes and insulin resistance, a new study shows.

"Resveratrol makes you look like a trained athlete without the training."

What is Resveratrol?

For years, people have been marvelling at extended life expectancies of Europeans who drink red wine daily. Now the secret has been uncovered. Resveratrol has been at the center of ground-breaking anti-aging research and more recently, has been provided in a purified form for daily consumption.

Resveratrol is an all natural supplement with some of the highest level anti-oxidants on the market. It is commonly found in Red Wine through grape pulp. Rich molecules provide a natural detoxification of muscle and fat tissue that are caused by years of build up due to airborn and terrestrial toxins. By consuming a safe daily dose of Resveratrol, you can start the break down process which will naturally help shed pounds and trim fatty areas.

Clinical Research

Studies at Harvard Medical School and the Institute of Genetics and Molecular Biology have found that resveratrol, a natural compound found in the skin of red grapes and hence in red wine, may radically reduce the risk not only of heart disease but also of age related illnesses such as Alzheimer's disease. It might also counter the effects of a high-fat diet and even prolong life."

Howitz and Sinclair reported in 2003 in the journal Nature that resveratrol significantly extends lifespan.

2006, Italian scientists obtained the first positive result of resveratrol supplementation.

2006, Sinclair reported resveratrol counteracted the detrimental effects of a high-fat diet.

2008, researchers at the Weill Medical College of Cornell University reported that dietary supplementation with resveratrol significantly reduced plaque formation in animal brains.